Vida-Defense Supports Healthy Immune Cell Function

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Research

Although the body is equipped with several defenses against foreign invaders and pathogens, a healthy immune system is not necessarily exempt from extrinsic visitors. With irrefutable evidence of the potential benefits of foods rich in antioxidants, prevention is at the forefront of medical advancement. Antioxidants have even reserved a therapeutic space in the treatment of chronic disease, usually supplemental to more invasive treatments.

Vida-Defense is a blend of powerful systemic enzymes and antioxidant herbs designed to support normal cellular metabolism and optimal immune function.

The unique blend found in Vida-Defense includes a potent, proprietary blend of plant and microbial proteases SEBPro® V. This is combined with a powerful blend of antioxidant, antimicrobial and immuno-stimulatory enzymes and herbs, including lysozyme, amylase, rutin, chitosanase, catalase, lipase, grapeseed extract and amla extract for complete, broad-spectrum defense.

Benefits of Vida Defense

Vida-Defense is an innovative and powerful enzyme blend formulated to maintain and support the body’s immune system by reducing free radical damage, inhibiting pathogens and providing nutritional and enzymatic support.

A unique proprietary blend of plant and microbial proteases (SEBPro VII) plays the most significant role in Vida-Defense by reducing inflammation, and supporting the body’s natural response to injury or infection. Inflammation is a sign of an abnormal metabolic pathway, used by the body as a reactionary mechanism to injury or illness, which results in a deposit of insoluble proteins. Vida-Defense’s anti-inflammatory proteases help break down these proteins, promoting quicker healing and reducing the severity of the condition.

Vida-Defense incorporates multiple potent antioxidants, including catalase, grapeseed extract and rutin. These components aid in the reduction of Reactive Oxygen Species (ROS), or free radicals, which severely damage cells and lessen their integrity. These powerful antioxidants reduce susceptibility to infection and allow cellular processes to remain focused on proper immune functions.

Vida-Defense includes several antimicrobial enzymes, giving this powerful formula a multifaceted approach to building immunity. Lysozyme, lactoperoxidase and chitosanase work on invading pathogens by breaking down their cellular wall components, making them more vulnerable to immune responses.

The proprietary blend found in Vida-Defense provides an all-encompassing formula for supporting normal cellular metabolism and optimal immune function.

Vida-Defense’s Antioxidant Benefits:

Amla:

Emblica officinalis Gaertn. or Phyllanthus emblica Linn, commonly known as Indian gooseberry or amla, is arguably the most important medicinal plant in the Indian traditional system of medicine, the Ayurveda. Various parts of the plant are used to treat a range of diseases, but the most important is the fruit. The fruit is used either alone or in combination with other plants to treat many ailments such as common cold and fever; as a diuretic, laxative, liver tonic, refrigerant, stomachic, restorative, alterative, antipyretic, anti-inflammatory, hair tonic; to prevent peptic ulcer and dyspepsia, and as a digestive. Preclinical studies have shown that amla possesses antipyretic, analgesic, antitussive, antiatherogenic, adaptogenic, cardioprotective, gastroprotective, antianemia, antihypercholesterolemia, wound healing, antidiarrheal, antiatherosclerotic, hepatoprotective, nephroprotective, and neuroprotective properties. In addition, experimental studies have shown that amla and some of its phytochemicals such as gallic acid, ellagic acid, pyrogallol, some norsesquiterpenoids, corilagin, geraniin, elaeocarpusin, and prodelphinidins B1 and B2 also possess antineoplastic effects. Amla is also reported to possess radiomodulatory, chemomodulatory, chemopreventive effects, free radical scavenging, antioxidant, anti-inflammatory, antimutagenic and immunomodulatory activities.

http://www.ncbi.nlm.nih.gov/pubmed/21317655

Grape Seed Extract (GSE)

In vitro studies show that GSE reduces oxidized low-density lipoprotein and is an even more potent scavenger of free radicals than vitamin E and vitamin C. Animal studies have also shown that GSE attenuates the development of atherosclerosis in cholesterol-fed rabbits. Findings conclude that GSE effectively amelioriates the inflammatory response in humans, suggesting that the consumption of GSE may be beneficial in atherosclerosis.

GSE has been successful in enhancing memory retention as evident by percent retention capacity in animal studies. The improvement of learning and memory, especially in the middle-aged animals suggests that grape seeds may increase the rate of hippocampal cells formation and develop receptors for neurotransmitters. Age-associated decline in learning and memory may be related to the altered metabolism in response to increased oxidative stress experienced by the hippocampal neurons. GSE may impact these hippocampal neurons either by altered storage or through chemical or structural components.

CL Chao, NC Chang, CS Weng, et al. Grape Seed Extract Ameliorates Tumor Necrosis Factor-a-Induced Inflammatory Status of Human Umbilical Vein Endothelial Cells. Eur J Nutr 2011. 50:401-409.

Asha Devi S, Sagar Chandrasekar BK, Manjula KR, Ishii N. Grape Seed Proanthocyanidin Lowers Brain Oxidative Stress in Adult and Middle-Aged Rats. Experimental Gerontology 2011. 46:958-964.

 Lysozyme:

Oral administration of lysozyme has been shown to positively affect immune responses in animal subjects by activating phagocytes and other cell-mediated responses.

The hypothesis described suggests that it may be proteolysis of intestinal microorganisms that makes the immune competent cells work in an immunostimulatory manner. The hypothesis is largely formed by several scientific observations:

1.      Microbial lysis products are well known for their immunostimulatory action.

2.      A normal human being hosts a mass of intestinal microorganisms equivalent to about 1 kg. The biomass (mainly due to naturally occurring autolysis) continuously supplies the host's organism with immunostimulatory microbial cell components.

3.      The immunostimulatory effects resulting from the oral application of exogenously acting antimicrobial (lytic) enzyme preparations, such as lysozyme are likely to be a result of the action of microbial lysis products.

4.      Cell walls of most microorganisms contain a considerable amount of proteins/peptides, a possible target for exogenous proteolytic enzymes. In fact, several authors have already shown that a number of proteases possess an ability to lyse the microbial cells in vitro.

5.      The pretreatment of microbial cells (at least of some species) in vitro with proteolytic enzymes makes them more sensitive to the lytic action of lysozyme and, otherwise, pretreatment with lysozyme makes them more susceptible to proteolytic degradation. 6.

6.      Exogenous proteases, when in the intestines, may participate in final steps of food-protein digestion. The resulting food-borne peptides have recently been shown to be potential activators of microbial autolysis.

http://www.ncbi.nlm.nih.gov/pubmed/16870353

Rutin

Rutin has been reported to exert numerous biochemical and pharmacological activities, such as free-radical scavenging and effects on immune and inflammatory cell functions. Rutin may also be beneficial in amyloid-related brain damage, by mitigating age-associated cellular damage induced via metabolic production of reactive oxygen species. Rutin has the ability to scavenge free-radicals, and suppress microglial activation and pro-inflammatory cytokines. There are several investigations which prove rutin’s neuroprotective ability and its anti-inflammatory activity in chronic conditions like arthritis.

http://www.sciencedirect.com/science/article/pii/S1043661803002251

http://www.sciencedirect.com/science/article/pii/S0306452212001893

FAQ

What is systemic enzyme therapy?

Systemic enzyme therapy refers to the therapeutic use of natural enzymes to produce desired healing effects. Systemic enzymes are absorbed from the small intestine where they enter the bloodstream and execute their effects on the entire body as a system. As an immune health enzyme, Vida-Defense is designed to help breakdown tough, damaging tissue. Providing the antioxidants required for supporting a strong immune system, Vida-Defense protects against inevitable free-radical damage by our daily environment.

What is a systemic proteolytic enzyme?

Proteolytic enzymes break down proteins into their building-blocks, which are called amino acids. Systemic proteolytic enzymes are responsible for breaking down accumulated protein and waste substances found in the circulatory system and connective tissue. Waste materials produced from inflammation and other biochemical processes can build up, contributing to excessive scarring and perpetuated immune responses. Excessive scarring, particularly of the organs, can exacerbate symptoms of the associated disease. The waste product of specific concern is known as fibrin. Regular systemic proteolytic enzyme use can improve circulation and aid in flushing out these waste products.

Are systemic enzymes anti-inflammatory drugs?

Although systemic enzymes produce anti-inflammatory effects, they are not considered a drug. Since enzymes are naturally occurring within the body, systemic enzyme therapy is considered supplementation. One difference between systemic enzymes and NSAIDs (Non-steroidal anti-inflammatory drugs) involves the duration of action. While NSAIDs produce short-term pain relief, systemic enzymes can produce long-term alleviation with appropriate use. The largest difference between NSAIDS and systemic enzymes is the mechanism of action and possible side effects. NSAIDs block the production of prostaglandins, which are responsible for inflammation and swelling. However, prostaglandins protect the lining of the stomach, and prolonged use of NSAIDs can reduce this protection and increase the risk of developing ulcers. Conversely, regular use of systemic enzymes has no negative side effects and can actually provide protective effects against excess inflammation.

How long should I take Vida-Defense before feeling results?

Since people experience varying ailments and severity of disease, the length of time to include systemic enzymes in your regimen may vary as well. As an overall guideline, it is typically recommended that new systemic enzyme users start off slow. A starter dose is generally one capsule, three times daily. After three to four days of proven tolerance, the dose can be increased to a therapeutic dose of 2 capsules, 3 times per day. At this point, results may be monitored, and dosage should be adjusted accordingly. Some consumers find their therapeutic dose between 6 to 9 capsules per day, while others only need 3. There are several factors that may affect results and required dosage, including:

• Height
• Weight
• Age
• Severity of symptoms
• Tolerance
• Time of administration (Better absorbed on an empty stomach)
• Adherence to regimen
• Nutritional state

What if I miss a dose?

Regular, consistent use of systemic enzymes will provide the best results, however missed doses of systemic enzymes do not have serious repercussions. Although symptoms alleviated by systemic enzyme therapy may resurface, getting back on track by remembering to take your next dose will suffice. There is also the option of incorporating another dose during the day. There is no need to “double up,” on one dose - and remember, systemic enzymes are best absorbed on an empty stomach.

Why is it important to take Vida-Defense on an empty stomach?

Since most absorption occurs in the small intestine, the systemic enzymes must bypass the stomach to gain access there. If the enzymes are taken with food, they will likely begin working to break down your food within the stomach, rather than passing through to the small intestine. Taking systemic enzymes like Vida-Defense with food will compromise their absorption, as well as their effectiveness.

Are there any side effects involved with Vida-Defense?

The use of Vida-Defense has not been shown to exhibit detrimental effects, neither long term nor short term. Just as dosage requirements vary, side effects may vary as well. Although gastrointestinal disturbances have been reported by a small percentage of new users, tolerance is maintained once the dosage is adjusted. There are no known interactions with prescription or over the counter drugs while using systemic enzyme therapy. However, it is recommended that you consult with your physician about starting systemic enzymes, especially if you are currently on blood-thinning medications or if you are pregnant or nursing.

What does “proprietary blend” mean?

Proprietary refers to a patent, or ownership. Applying this concept to our enzyme blends, it means that we alone own the rights to the specific blend of enzymes found in Vida-Defense, making our product different from similarly marketed digestive enzyme supplements. Vida-Defense encompasses an all-inclusive immune health blend that simultaneously assists in the breakdown of pathogenic tissue and stimulation of the body’s natural defenses.

Can I take Vida-Defense with other systemic or digestive enzymes?

Although digestive and systemic enzymes arenot contraindicated in terms of ingredients, they cannot be taken at the same time. The purpose of digestive enzymes is to aid in digestion of specific foods, so taking them with food is an obvious recommendation. Because systemic enzymes require an empty stomach for maximum absorption, they must be taken separately from digestive enzymes. There are no adverse interactions between systemic and digestive enzymes, but they serve different purposes and thus should be taken as directed for best results.